Integrative Veterinary Oncology 2501 N. 32nd Street
Phoenix, AZ 85008
P: 602.841.0626
F: 602.995.7048

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Western Medicine: Cryosurgery - Immunotherapy - Photodynamic Therapy - Cold Laser Therapy
Prolozone Therapy - Ultraviolet Blood Irradiation Therapy

What is Ozone?

Oxygen as a single atom is deficient in electrons . This makes the atom very unstable and as a result single oxygen atoms are not able to exist in nature. Two oxygen atoms can join together and share electrons to form the very stable molecule known as O2. This is the stable form of oxygen in the atmosphere that we breathe. When an energetic force such as electricity or ultraviolet light is imposed upon a molecule of O2, the molecule will split apart into single oxygen atoms. These oxygen molecules will quickly pair back up into the O2 molecule but a few of them will form a trio known as ozone. Thus, ozone, known as O3 is a molecule made up of 3 oxygen atoms sharing the same electrons. Ozone is a relatively unstable molecule but that is why it is so powerful! In a matter of minutes, the ozone molecules will react with each other to form the more stable O2 molecule, a process known as dismutation. Once ozone has been generated for a medical application, it must be used rather quickly. It cannot be stored and used for later.

How is Ozone Made?

Ozone is made by passing pure oxygen gas through a tube through which energy is directed. The energy breaks apart the molecules such that both oxygen and ozone is generated on the other side. Ozone cannot be made from room air as room air also contains Nitrogen which is converted to nitrous oxide and nitric oxide through the energy tube, both of which are highly toxic. Thus, the ozone used for medical purposes is generated from high quality pure oxygen.

What Conditions can Ozone Treat?

Any chronic, degenerative disease can benefit from ozone therapy including diabetes, cancer, osteoarthritis, chronic infectious disease, inflammatory diseases, cardiovascular diseases, autoimmune disease, immunodeficiency disorders, and chronic and acute pain. Ozone therapy may be thought of a homeopathic therapy, that is a therapy that stimulates and stabilizes biological functions, rather than suppressing them. Ozone therapy itself does not cause the healing effect but rather induces the body’s own innate healing mechanisms. Thus, it may be used successfully in any medical condition regardless of the western medical diagnosis. Ozone therapy is not typically a “stand” alone therapy but used with other treatment modalities including acupuncture, nutrition, herbs, and allopathic (western) medication.

How is Ozone Administered?

There are several ways in which ozone therapy may be administered to a patient. The most common applications are blood transfusion (major autohemotherapy) or rectal insufflation. Other methods include bladder insufflation, limb bagging, topical application or injection ,isode therapy and sauna.

Major autohemotherapy involves removal of a specified amount of blood (50-250 ml depending on the size of the patient) from a patient, treatment of the blood with ozone and then transfusion back into the patient. This requires a minimum of 4 hours for completion of therapy. This method is ideal for systemic conditions including cancer, auto-immune diseases, immunodeficiency diseases, infectious disease, inflammatory disease and pain.

Minor autohemotherapy involves the removal of a small amount of blood (1-2 mls), treatment with ozone and injection back into the patient via the intramuscular route. This may also be used for systemic conditions as with major autohemotherapy as well as allergies.

Limb bagging involves isolation of an extremity with a plastic bag and infusing humidified ozone into the bag. This technique is useful for wounds, decubital ulcers, diabetic ulcers and localized infections.

Intralesional injection involves injection of ozone directly into a tumor to encourage tumor cell kill and reduction of the mass. Another technique involves injection of saline into a tumor and then withdrawal of the fluid, incubation with the patient’s own blood for 24 hours and then reinjection of the tumor/blood solution directly into the tumor. This can cause priming of the immune system and reduction in tumor size.

Rectal insufflations involves instilling 50-500 cc of ozone gas into the rectum and having the patient maintain the ozone for maximum of 40 minutes. This method is useful for any system illness and is often administered 1-2 times per week initially and then tapered to once per month.

Bladder insufflation involves instilling 50-150 cc of ozone gas into the bladder. This method may be used for chronic cystitis and bladder cancer.

Urine/Blood Isode Injections involves processing of the patient’s blood and urine with ozone for intramuscular injection. UB Isode injections are useful for activating or enhancing the body’s cellular mediated immune response in patients with cancer, chronic infections, allergies and autoimmune diseases. These injections are typically administered twice per week for 4 weeks, then once per week, ultimately tapering to once per month.

Ozonated Water- Ozonated water is water that has been treated with ozone. It can purify water without leaving any harmful chemicals behind. The benefits of ozonated water include purification of blood (kills bacteria and viruses), “clean” the circulatory system by reducing the bunching up of red blood cells in the capillaries, improve oxygenation of body tissues and function, and potentially break down and oxidize tumors.

Ozonated Olive Oil is made by bubbling ozone continuously through olive oil for 3 weeks until it becomes a paste or salve. We do not make our own olive oil but purchase it premade from Longevity. Ozonated olive oil is an effective adjunct treatment for inflammation of the skin, such as dermatitis and seborrhea. Ozonated olive oil is helpful in bacterial infections of the skin, including cellulitis, ecthyma, folliculitis, ringworm, skin yeast, staphylococcus, and sweat gland infections. It is also helpful for bed sores (decubitus ulcers) and for the post-surgical treatment of wounds to prevent secondary infections. It may also be helpful for treating superficial dermal tumors.

How often are the treatments?

Ozone therapy may be administered as frequently as twice per week depending on the patient’s symptoms and response to therapy. Most patients will benefit from treatments every 1-2 weeks. Acute conditions may need 3-6 treatments to resolve. Patients with chronic conditions, including pain conditions may need ozone t herapy at every 1-2 month intervals long term.

Is Ozone Treatment Painful?

In the methods described above, ozone does not typically cause discomfort. However, a mild sedative/analgesic may be considered in certain patients should discomfort be experienced.


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